Clinical trial to prevent food allergies in children launched in UK first

A clinical trial which aims to prevent children from developing food allergies has been launched in a UK first.

Experts at Evelina London Children’s Hospital and King’s College London are opening the Stopping Eczema and Allergy (SEAL) trial which will be available for babies aged from birth to 12 weeks, if they have any signs of dry skin or eczema.

Previous research has shown that if a baby develops eczema before the age of three months, and needs to use prescribed steroids on the skin, they are 50 per cent more likely to develop food allergies as a child.

The SEAL trial aims to prevent children from developing a food allergy by restoring the skin barrier, to prevent the transfer of food allergens through the skin.

Dr Farhana Rahman’s eight-week-old daughter, Yusra, is currently being screened with the hope of starting the trial.

Dr Rahman, a GP from south Croydon, said: “My hope is that this trial could reduce the risk of my baby developing food allergies, something she may be at higher risk of since I have eczema and allergic conditions myself.

“As a mum I just want to do what’s best for my child, so I feel reassured knowing my baby and I will be in safe every step of the way.”

Each participant will be on the trial for two years, and during that time will be reviewed by the clinical team at Evelina London’s specialist allergy research centre. 

Participants will also be followed-up for food allergy testing annually until the age of two years.  

Helen Brough, Professor of paediatric allergy at Evelina London and King’s College London, and joint trial lead, said: “We’re pleased to be opening this new clinical trial, and hope it will make a difference for the next generation.”

If you would like your child to take part in the SEAL clinical trial or would like more information, please email gst-tr.sealstudy@nhs.net.

Pictured top: Farhana Rahman and her daughter Yusra in hospital (Picture: Farhana Rahman)